Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

This study is testing a drug called edecesertib to see if it helps people with Cutaneous Lupus Erythematosus (CLE). CLE is a skin condition that causes red, scaly patches. The study will also look at what happens in the body because of CLE and how the drug affects it, including any side effects. To join, you need to have CLE with skin affected in two places and be willing to have skin biopsies, which are small samples taken from your skin.

• The study will check if you can tolerate or respond to other treatments before.
• If you have other active skin conditions, you cannot participate.
• You must attend all visits and follow the study instructions closely.