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Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine

Studying erenumab's effects on migraines in children.

Recruiting
6-17 years
All
Phase 3

This study looks at how well and safely the medicine Erenumab works to prevent migraines in kids and teens. Migraines are bad headaches that can make you feel sick and sensitive to light or sound. The study is for children aged 6 to 18 who have these headaches sometimes, not all the time. Placebo is a fake medicine used to compare with the real medicine to see which works better.

The study has four parts:

  • Screening: Up to 7 weeks to check if you can join.
  • Double-blind Treatment Phase (DBTP): 12 or 24 weeks to test Erenumab or placebo.
  • Optional Extension Phase: 40 weeks where everyone gets Erenumab.
  • Follow-up: 12 weeks to see if you're okay after stopping the medicine.

Key Points:

  • This study lasts more than one year, with several visits needed.
  • Participants will get injections once a month.
  • There may be risks, like side effects from the medicine.

Note: 456 participants are planned to join. You need permission from a parent or guardian to participate.

Study details
    Migraine

NCT03836040

Amgen

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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