Peripheral Artery Disease (PAD) is a condition where plaque builds up in arteries, blocking blood flow, especially to the legs. This can cause pain and numbness, more so during exercise. The study aims to see if a drug called Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) can help improve symptoms in people with PAD. GM-CSF encourages bone marrow to release stem cells, potentially aiding blood flow. Participants will either get GM-CSF or a placebo, which is a harmless pill with no active medication. They will receive injections three times a week for three weeks, take a break, and then get another three-week course after three months. There will be follow-ups for six months to check for improvements.

• Duration: Study lasts 6 months with injections and follow-ups.
• Visits: Participants must attend regular visits for injections and evaluations.
• Eligibility: Specific health criteria must be met, such as documented PAD and stable medication use.

Participants should be aware of potential risks and must meet specific health criteria to join the study.