This study is about helping people with severe depression. The researchers are looking at two types of Electroconvulsive Therapy (ECT), a treatment that uses electrical currents to help improve severe depression. ECT can cause some memory problems, but a new way called Frontoparietal UBRUL ECT might help with fewer side effects.

To join, you must be at least 18 years old, diagnosed with major depression, and able to follow the study rules. You cannot join if you have certain mental health issues, substance abuse problems, or recent ECT treatment.

• Study Length: The study involves treatment for about 4 weeks and a follow-up for 24 weeks.
• Treatment: Participants will receive 12 ECT treatments, but the number can change based on doctor advice.
• Risks: There may be some memory problems, but the new method might reduce these side effects.

This study compares two ECT methods to see which is more effective and safer. If you have severe depression and meet the criteria, this study could potentially help you, but it’s important to consider the time commitment and possible side effects.