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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

TAPUR: Testing FDA-approved drugs for specific tumor gene abnormalities.

Recruiting
12 years and older
All
Phase 2

The TAPUR study focuses on advanced cancer patients. Researchers are testing drugs that are approved by the Food and Drug Administration (FDA) to see if they work on tumors with special gene changes. These gene changes make some cancers sensitive to certain medications. The study is *non-randomized*, meaning patients receive specific treatments based on their tumor's genetic profile, not by chance.

Key Points:

  • Participants need to be 12 years or older and have a specific type of cancer that no longer benefits from standard treatment.
  • Patients must have a genetic test showing they might benefit from one of the study drugs.
  • Participants will need to agree to regular doctor visits and follow the study guidelines.

To join, patients must have a measurable tumor and good organ function. They should be able to swallow pills, and women must use birth control. Some patients, like those with brain tumors or who can't have their cancer measured, may not be eligible. To learn more, contact your local TAPUR site or email TAPUR@asco.org.

Study details
    Lymphoma
    Non-Hodgkin
    Multiple Myeloma
    Advanced Solid Tumors

NCT02693535

American Society of Clinical Oncology

1 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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