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STK-012 Monotherapy and in Combination Therapy in Patients with Solid Tumors

Study of STK-012 alone or with Pembrolizumab for solid tumors.

Recruiting
18 years and older
All
Phase 1

Study Overview: This study is testing a new medicine called STK-012 for people with solid tumors, which are lumps of cancer that don't have a liquid form. It is in phase 1, which means it is the first time the medicine is being tested in humans to check how safe it is and to find the right dose. The study will also see how well STK-012 works alone and when given with another cancer medicine called pembrolizumab.

Key Definitions: A multicenter, open-label study means it is being done at different places, and everyone knows what medicines are being taken. Dose escalation is a process to find the safest and best dose of the medicine by slowly increasing it.

  • Participation Requirements: You must have a specific type of tumor that got worse after usual treatments.
  • Study Details: You might need to give a new tissue sample for testing.
  • Exclusions: You cannot join if you've had other cancer treatments recently.
Study details
    Advanced Solid Tumor
    Non Small Cell Lung Cancer
    Head and Neck Squamous Cell Carcinoma
    Malignant Melanoma
    Renal Cell Carcinoma
    Cervical Cancer
    Microsatellite Instability High
    Gastric Cancer
    GastroEsophageal Cancer
    Urothelial Carcinoma
    Mismatch Repair Deficiency

NCT05098132

Synthekine

13 December 2024

Step 1 Get in touch with the nearest study center
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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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