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Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

Study on new HIV treatment vs. current complex therapy.

Recruiting
18 years and older
All
Phase 2/3

This study aims to compare new HIV medications, bictegravir (BIC) and lenacapavir (LEN), with current treatments for people with HIV-1. HIV-1 is a type of virus that attacks the body's immune system. The study is in two phases, with Phase 2 focusing on switching to BIC and LEN, and Phase 3 testing a fixed-dose combination of these drugs. To join the study, participants must have a stable HIV-1 condition, shown by low virus levels in their blood, and be on a complex treatment plan for at least 6 months. A complex plan might mean taking multiple pills daily or having experienced resistance to simpler treatments. Participants should not have used LEN before and shouldn't have certain infections like tuberculosis or hepatitis B.

Key Points:

  • Study involves switching current HIV treatment to new medications.
  • Participants must have low HIV levels and a complex treatment history.
  • Some infections disqualify participation, such as tuberculosis and hepatitis B.
Study details
    HIV-1-infection

NCT05502341

Gilead Sciences

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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