Study Overview: This study checks how two types of birth control tablets, LF111 and drospirenone (also called DRSP), affect bone health in women. Bone Mineral Density (BMD) checks the strength of bones. The study compares these tablets to non-hormonal birth control methods over 12 months. It also looks at safety, body fat, and muscle changes.

Eligibility: Female participants should be aged 14 to 45, not pregnant, and have regular periods. Some health conditions, like certain bone or liver diseases, might exclude you from participating. The study is split into two age groups: 14-17 and 18-45.

• Duration: The study lasts 12 months with visits at the start, 6 months, and 12 months.
• Participation: You'll need to take tablets or use non-hormonal methods for 13 cycles.
• Safety: Regular check-ups are done to ensure participant safety.

If you're interested, you must give written consent before starting. This study helps understand how these birth control methods affect bone health and overall safety. Participants are not randomized, so you can choose your preferred method.