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Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Study to assess safety and effects of INX-315 in advanced cancer patients.

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at a new medicine, INX-315, for people with advanced cancer. The study has three parts and is open-label, meaning doctors and patients know what treatment is given. INX-315 is a small molecule that stops a protein called CDK2 which helps cancer cells grow. This study checks if the medicine is safe and how it works in the body.

In Part A, about 60 patients, with different types of cancer like breast and ovarian cancer, will try different doses of INX-315 to find the best dose. Part B focuses on ovarian cancer and will involve at least two doses. Part C tests INX-315 with other medicines for breast cancer patients.

  • Study includes regular visits and tests over several months.
  • Participants must have advanced cancer and meet specific health criteria.
  • Potential side effects and risks, but also a chance to help find new treatments.

Talk to your doctor if you are interested in joining. They will help decide if this study is right for you based on your health and cancer status.

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Study details
    Breast Cancer
    Breast Cancer Metastatic
    Hormone Receptor Positive Tumor
    Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
    Ovarian Cancer
    CCNE1 Amplification
    Solid Tumor
    Advanced Cancer
    Metastatic Cancer

NCT05735080

Incyclix Bio

13 December 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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