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A Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas

Exploring CPI-0209 effects in advanced cancer and lymphoma patients.

Recruiting
18 years and older
All
Phase 1/2

Study Overview: This is a research study to test a new drug called CPI-0209 in people with advanced cancer or lymphoma. CPI-0209 is a special type of medicine that blocks a protein called EZH2 which is sometimes found in high amounts in cancer cells. The study has two parts (Phase 1 and Phase 2) to see if the drug is safe and how well it works.

Phase 1: This part is to find the best dose of CPI-0209 that can be given safely. People who join this part have cancers that didn't respond to regular treatments.

Phase 2: This part will test the drug in specific types of cancer in different groups of patients to see how well it works and how safe it is. There will be multiple groups (cohorts) with different types of cancers.

  • Study Duration: The study involves multiple phases, possibly lasting several months.
  • Who Can Join: Adults with advanced cancer or lymphoma, after other treatments didn't work.
  • Compensation: Participants may receive compensation for their time and travel.
Study details
    Advanced Solid Tumor
    Diffuse Large B Cell Lymphoma
    Lymphoma
    T-Cell
    Mesothelioma
    Malignant
    Prostatic Neoplasms
    Castration-Resistant
    Endometrial Cancer
    Ovarian Clear Cell Carcinoma

NCT04104776

Constellation Pharmaceuticals

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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