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Testing the Combination of Inotuzumab Ozogamicin and Lower Dose Chemotherapy Compared to Usual Chemotherapy for Adults with B-Cell Acute Lymphoblastic Leukemia or B-Cell Lymphoblastic Lymphoma

Comparing new and usual treatments for B-Cell leukemia or lymphoma.

Recruiting
50 years and older
All
Phase 2

This study is exploring a new treatment for adults with certain types of blood cancer, called B-cell acute lymphoblastic leukemia (ALL) or B-cell lymphoblastic lymphoma (LBL). The new treatment combines a drug called inotuzumab ozogamicin with lower doses of traditional chemotherapy. Inotuzumab ozogamicin is a special medicine that finds and attacks cancer cells, thanks to a part called a monoclonal antibody. This study compares this new combination to regular chemotherapy to see which works better.

  • Participants are placed in one of two groups: one receiving the new treatment and the other receiving standard chemotherapy.
  • The study lasts up to two years, with regular checkups to monitor progress and health.
  • Patients will have follow-up visits every few months after completing the treatment.

Eligible participants must be 50 years or older, have a confirmed diagnosis of B-cell ALL or LBL, and meet specific health criteria. The study aims to measure how well the cancer responds to the treatment and check for any side effects. Be sure to discuss with your doctor if you are interested in participating, to understand potential benefits and risks.

Study details
    B Acute Lymphoblastic Leukemia
    B Lymphoblastic Lymphoma

NCT05303792

Alliance for Clinical Trials in Oncology

18 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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