Image

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Study on ibrutinib and indoximod for pediatric brain cancer treatment.

Recruiting
6-25 years
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for children and young adults, aged 6 to 25, who have certain types of brain cancer that have not responded to other treatments. The study will test a new cancer treatment that combines two drugs, ibrutinib and indoximod, with chemotherapy. Ibrutinib helps block cancer cell growth, while indoximod boosts the immune system to fight cancer. This treatment is designed to work better against cancer than using just one drug alone.

  • Study involves taking pills and requires the ability to swallow them.
  • Participants must not be pregnant or breastfeeding, and must use effective birth control.
  • Regular visits to the study center for check-ups and treatment are needed.
Print
Study details
    Ependymoma
    Medulloblastoma
    Glioblastoma
    Primary Brain Tumor

NCT05106296

Theodore S. Johnson

15 March 2025

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.