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DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Join a study testing BI 764532 doses for advanced lung cancer.

Recruiting
18 years and older
All
Phase 1

DAREONᵀᴹ-8 Study is for adults with a type of lung cancer called **extensive stage small cell lung cancer (ES-SCLC)**. The study tests how well people handle doses of a new drug, BI 764532, when combined with **standard of care (SoC)** treatments like chemotherapy and immunotherapy. BI 764532 is an antibody-like molecule, which means it might help your immune system fight cancer. The drug and SoC treatments are given through a needle into a vein.

The goal is to find the highest dose of BI 764532 that people can handle without too many side effects. If participants feel better and can tolerate the treatment, they will continue with it for the study's duration. Participants will regularly visit the study site, where doctors will check their health, run lab tests, and watch for any problems caused by the treatment.

  • The study is only for people who have not had systemic treatment for ES-SCLC before.
  • Participants need to visit the study site regularly for health checks.
  • The study is open only to adults over 18 years old.
Study details
    Small Cell Lung Carcinoma (SCLC)

NCT06077500

Boehringer Ingelheim

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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