This study is looking at how chemotherapy, a type of strong medicine that kills cancer cells, works best when given to people with pancreatic cancer that can be removed by surgery. The study compares two ways of giving chemotherapy: one group gets it before and after surgery (called perioperative), and the other only after surgery (called adjuvant). This will help doctors understand if giving chemotherapy both before and after surgery helps patients live longer and better.

• Duration: After finishing treatment, patients are followed up for 6 years.
• Visits: Patients have regular medicine treatments every 14 days during the study.
• Eligibility: You must not have had prior treatment for pancreatic cancer and should not be pregnant or nursing.

Patients will receive medicines like oxaliplatin, irinotecan, leucovorin, and fluorouracil through a vein. There are specific requirements to join the study, including health checks to ensure safety. By participating, you help researchers discover better ways to treat pancreatic cancer.