This study is about testing a special cream called ruxolitinib for adults with moderate atopic dermatitis (AD), a condition that makes your skin itchy and red. The cream is being tested on people who haven't found other creams like topical corticosteroid (TCS) or topical calcineurin inhibitor (TCI) helpful or they can't use them.

To join, you should be 18 or older and have had AD for at least 2 years, with a specific level of skin involvement and itchiness. You shouldn't join if your AD changes rapidly, if you have certain infections, or if you have been on some strong medicines recently. You also need to be ready to stop using other AD treatments during the study.

• The study involves using ruxolitinib cream on your skin as directed.
• You will need to visit the study site for check-ups and follow the study rules closely.
• The study will check if the cream helps your skin and is safe for you to use.

It's important to talk to your doctor to see if joining the study is a good choice for you.