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Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Exploring TSR-042 for advanced solid tumors treatment.

Recruiting
18 years and older
All
Phase 1

This study is for adults with advanced solid tumors, which are cancerous growths that have spread. It tests a new drug called dostarlimab, which helps the body fight cancer. The study has two parts: the first part finds a safe dose, and the second part sees how well it works in different cancers. Dostarlimab will be given in different doses to see which works best and is safe. Some people will get a dose every 3 weeks, and others every 6 weeks.

  • The study lasts several weeks, with regular visits for treatment and check-ups.
  • Participants may receive dostarlimab at different doses to find the best one.
  • There may be risks, as the study involves a new drug, but it could help treat cancer.

To join, you must have tried other cancer treatments that didn't work, and meet specific health criteria. People with certain health issues or previous treatments can't participate. This study might help find a new treatment for cancer, but there are potential risks involved. Always discuss with your doctor before joining a study.

Study details
    Neoplasms

NCT02715284

Tesaro, Inc.

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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