This study is for adults over 40 with Chronic Obstructive Pulmonary Disease (COPD), a lung condition making it hard to breathe. We are testing a medicine called Tozorakimab, given as a shot under the skin, to see if it helps people with COPD who often have flare-ups. Participants should already be using inhaled medicines. To join, you need a diagnosis of COPD for at least a year, have had breathing troubles in the past year, and a history of smoking. You cannot join if you have other serious lung diseases or a recent history of severe illness like COVID-19.

• This study will measure both the safety and efficiency of the new medication, Tozorakimab.
• Participants need to visit the study site at specific intervals for check-ups and to receive the medication.
• There may be risks like side effects, and you should discuss these with the study team.