This study examines a new way to heal serious burn wounds using a product called realSKIN®. It is being tested as an alternative to autografting, which is when a doctor takes healthy skin from one part of your body to cover the burn. This study is a Phase 3 clinical trial, meaning it's in the later stages of testing with people. Participants include about 50 men and women who are 18 or older with severe burns. They will receive both realSKIN® and autografting on different wounds to compare how well each method works.

• The study lasts several months, and participants must be willing to have two types of treatments on different wound areas.
• You must not be pregnant or have certain health conditions to participate.
• Participants will receive a skin treatment that is new and still being studied for safety and effectiveness.

Only people with burns on less than 50% of their body and who meet other health criteria can join. If you participate, you'll help researchers learn more about new treatments for burn wounds.