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Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Study comparing two maintenance treatments for ovarian and related cancers.

Recruiting
18 years and older
All
Phase 3

This study is testing a new treatment called Mirvetuximab Soravtansine for women with certain types of cancer: ovarian, fallopian tube, or peritoneal. These cancers are platinum-sensitive, meaning they respond well to a type of chemotherapy. The study compares the new treatment with another called Bevacizumab, which is already used. Mirvetuximab Soravtansine is a special medicine that targets cancer cells with high amounts of a protein called folate receptor-alpha (FRα). If you join, doctors will check if your cancer has this protein. To join, you must be over 18, have had some specific treatments before, and meet other health requirements.

  • Study duration and number of visits: Participants will receive treatment until the disease progresses or they experience unacceptable side effects.
  • Compensation: Participants may receive reimbursement for travel or other study-related expenses.
  • Risks: Possible side effects may include fatigue, nausea, and low blood counts.

It's important to discuss participation with your doctor to understand all potential risks and benefits. You must agree to use birth control during the study if you're capable of having children, and you can't join if you're pregnant or breastfeeding.

Study details
    Ovarian Cancer
    Peritoneal Cancer
    Fallopian Tube Cancer

NCT05445778

AbbVie

13 December 2024

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  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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