Parkinson's and Zoledronic Acid Study is a home-based test for people aged 60 and older with Parkinson's Disease (PD) or similar conditions. The study is testing if a medicine called Zoledronic Acid (ZA) can help prevent bone fractures. A total of 3,500 people in the U.S. will join, and they will either get ZA or a placebo (a fake treatment). The study is "blinded," meaning no one knows who gets ZA or the placebo except the main researchers. This study is funded by the National Institute of Aging.
To join, you must not have had a hip fracture, taken certain bone drugs recently, or had major dental work recently. The study lasts for at least 2 years, and you'll be checked every 4 months to see if you've had any fractures. If you qualify, a nurse will visit your home to give the medicine. Participants also get vitamin D pills to take daily for 2 months.
- Study lasts at least 2 years with regular follow-ups.
- Nurse visits your home for treatment, no extra doctor visits needed.
- Participants must be 60 or older and have Parkinson's or similar conditions.