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A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study on Ralinepag's effectiveness and safety for PAH patients.

Recruiting
18 years and older
All
Phase 3

This study is for adults with **pulmonary arterial hypertension (PAH)**, a type of high blood pressure affecting the lungs and heart. It checks if a new medicine, **Ralinepag**, helps patients when added to their usual treatments. Participants will take either Ralinepag or a placebo (a pill with no active medicine) along with their regular PAH treatments. The goal is to see how long it takes for a participant's condition to worsen.

Participants will be in the study for about 28 weeks. If their condition gets worse, they might switch to an extension study to keep getting the real medicine. People who don't want to continue can stop the study drug but will still be checked for their health status.

  • **Duration**: The study lasts for about 28 weeks.
  • **Eligibility**: Participants must be 18 or older and have symptoms of PAH.
  • **Safety**: Regular check-ups and tests will be done to ensure safety.

If interested, participants need to sign a consent form and agree to follow the study guidelines, including using birth control if needed. Some health conditions or prior treatments may prevent participation.

Study details
    PAH
    Pulmonary Hypertension
    Pulmonary Arterial Hypertension
    Hypertension
    Connective Tissue Diseases
    Familial Primary Pulmonary Hypertension
    Vascular Diseases
    Cardiovascular Diseases
    Hypertension
    Pulmonary
    Lung Diseases
    Respiratory Tract Disease

NCT03626688

United Therapeutics

8 March 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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