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Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Studying Ianalumab with standard treatment for lupus patients in Phase 3 trial.

Recruiting
12 years and older
All
Phase 3

This study is testing a new treatment called ianalumab for people with Systemic Lupus Erythematosus (SLE), which is a disease where the body's immune system attacks its own tissues. The study will compare the effects of ianalumab, given as a shot under the skin every month, to a placebo (a fake treatment), while participants continue their usual treatments. The study is double-blind, meaning neither the participants nor the researchers know who is getting the real treatment.

  • The study involves regular monthly visits to receive the injection.
  • Participants must be at least 12 years old, with some restrictions in certain countries.
  • Participants should not have received certain medications recently and must not have serious infections or organ problems.

This research aims to see if ianalumab is safe, effective, and how well people can tolerate it. If you're considering joining, think about the monthly visits and any potential risks mentioned above. Discuss with your doctor if this study might be right for you, especially if you meet the eligibility criteria and are interested in trying a new treatment for SLE.

Study details
    Systemic Lupus Erythematosus

NCT05624749

Novartis Pharmaceuticals

5 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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