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Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

Study on Ketorolac use before surgery for lung and kidney cancer.

Recruiting
18-80 years
All
Phase N/A

This study tests if a drug called **ketorolac** can help people having surgery for two types of cancer: non-small cell lung cancer (NSCLC) and renal cell carcinoma (RCC). Ketorolac is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It helps reduce inflammation, which is the body's response to injury. This study will see if taking ketorolac before surgery can lower the chance of cancer coming back and improve survival. Surgeons will give ketorolac to some patients before their surgery, while others will not receive it. Blood samples will be collected before and after surgery. The study includes 76 patients and lasts up to 28 days, with follow-ups at 1 and 2 years after surgery.

  • The study involves taking ketorolac before surgery to see if it helps prevent cancer from returning.
  • Participants will be randomly assigned to receive ketorolac or not and will have follow-up visits.
  • Eligibility includes having certain types of early-stage lung or kidney cancer and being able to give consent.
Study details
    Non-small Cell Lung Cancer
    Renal Cell Carcinoma

NCT04495894

Emory University

12 October 2024

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