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A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma

Comparing treatments for follicular lymphoma in a clinical study.

Recruiting
18 years and older
All
Phase 3

Study Overview: This study is testing a new treatment for follicular lymphoma (FL), a type of blood cancer. The study compares two combinations of medicines: Mosunetuzumab and Lenalidomide (M + Len) versus Rituximab and Lenalidomide (R + Len). Participants must have previously tried at least one other treatment for their lymphoma.

Inclusion Criteria: Participants must have a specific type of FL and be in good enough health to participate. They need to have had previous lymphoma treatment and be willing to follow guidelines to prevent pregnancy during and after the study.

Exclusion Criteria: People with certain medical conditions, like severe allergies or other types of cancer, cannot participate. Those who have had recent treatments or certain infections are also excluded.

  • Study Duration: This study involves multiple visits and treatments over time.
  • Risks: There may be side effects from the medications used in this study.
  • Compensation: Participants may receive compensation for their time and travel.
Study details
    Relapsed or Refractory Follicular Lymphoma

NCT04712097

Hoffmann-La Roche

5 January 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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