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Immunization With BCG Vaccine to Prevent Tuberculosis Infection

BCG vaccine may help prevent tuberculosis infection. Join our study!

Recruiting
18-65 years
All
Phase 3

BCG Vaccine Study: This study is to see if a BCG vaccine, given before travel, can help prevent tuberculosis (TB) in adults going to countries with high TB rates. The BCG vaccine from Japan is used worldwide but is experimental in the U.S., so it's being compared to a placebo, which is a fake vaccine that does nothing. About 2000 adults will join the study, and they'll be randomly chosen to get either the BCG vaccine or the placebo. The study is looking for changes in a test called the IGRA, which checks for TB infection.

  • The study needs 4 to 6 visits including checkups and follow-ups.
  • Participants should be 18-65 years old and in good health.
  • Participants may face side effects like reactions at the shot site.

Eligibility: Participants must be in good health, not have had TB or a BCG vaccine before, and be traveling to high TB risk countries for work. They must agree to use birth control if needed and not get other vaccines during the study period.

Study details
    Tuberculosis Infection

NCT04453293

Henry M. Jackson Foundation for the Advancement of Military Medicine

10 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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