Retinitis Pigmentosa (RP) is a genetic eye disease that causes night blindness and narrow vision over time. This happens because tiny parts of the eye that help you see in dim light, called rod photoreceptors, stop working. Later, other parts called cone photoreceptors also start to fail, leading to tunnel vision. Scientists believe that something called oxidative stress, which is like rusting inside the eye, makes this worse. N-acetylcysteine (NAC) is a medicine that can reduce oxidative stress. Early tests showed NAC might help slow down the damage to cone photoreceptors in people with RP. This study, called NAC Attack, will see if taking NAC for several years helps those with RP. It takes place in the US, Canada, Mexico, and Europe.

• The study will last several years and involves taking NAC orally.
• Participants must be 18-65 years old and able to attend all study visits.
• Some exclusions include recent cancer, liver or kidney disease, and specific eye conditions.