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A Study of Ponsegromab in People With Heart Failure

Researching Ponsegromab for heart failure patients.

Recruiting
18 years and older
All
Phase 2

This study is testing a new medicine called Ponsegromab for people with heart failure. Heart failure is when the heart can't pump blood as well as it should. The study compares Ponsegromab to a placebo, which is a fake injection that looks like the real medicine but doesn't have any active ingredients. Participants won't know if they're getting the real medicine or the placebo. Most people in this study will get an injection under the skin every four weeks for about nine months, visiting the study clinic monthly. Some people in a special group will only get Ponsegromab and will be in the study for about seven months.

Key Points:

  • Study lasts about 9 months for the main group, with monthly clinic visits.
  • Participants receive injections every four weeks.
  • There's a special group that only gets the study medicine for 7 months.

Before joining, participants must be 18 or older and have specific medical conditions. Some people can't join, like those who've had a heart transplant or certain recent surgeries. Participants also shouldn't have taken similar investigational medicines before.

Study details
    Heart Failure

NCT05492500

Pfizer

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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