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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Testing BMS-986393 safety and effects in multiple myeloma patients.

Recruiting
18 years and older
All
Phase 1

Study Purpose: This study aims to find a safe and effective dose of a new drug, BMS-986393, for patients with a type of blood cancer called multiple myeloma. This cancer has come back or does not respond to treatment, which is called relapsed or refractory. The study will combine BMS-986393 with other drugs, alnuctamab, mezigdomide, and iberdomide.

Who Can Join: Adults with relapsed or refractory multiple myeloma who have had at least one to three treatments for their cancer before. They must have cancer that can be measured and be in good physical health (able to do normal activities). People cannot join if they have brain or spinal cord involvement from their cancer.

  • **Participation Length:** Varies, based on treatment response.
  • **Compensation:** Available for travel and participation.
  • **Risks:** Potential side effects from drug combinations.

This study is looking to understand the safest way to help those with difficult-to-treat multiple myeloma.

Study details
    Multiple Myeloma

NCT06121843

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

5 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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