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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

The PedAL Trial: Testing Bone Marrow and Blood in Tough Leukemia Cases.

Recruiting
22 years and younger
All
Phase 1/2

This study is for young people with a type of cancer called leukemia that has come back after treatment or is hard to treat. Leukemia is a cancer of the blood and bone marrow, the spongy tissue inside bones where blood cells are made. The study will look at samples of blood and bone marrow to learn more about the cancer and find better ways to diagnose and treat it. Children, adolescents, and young adults under 22 years old who have specific types of leukemia can join this study. After joining, patients will have their samples collected at different times, and they will be checked every few months for up to 5 years. This will help doctors understand their condition better. Before joining, all participants and their guardians must agree and sign a consent form.

  • Length: Regular check-ups for up to 5 years.
  • Visits: Blood and bone marrow samples collected at different stages.
  • Eligibility: Under 22 years old with certain types of leukemia.
Study details
    Acute Lymphoblastic Leukemia
    Acute Myeloid Leukemia
    Acute Myeloid Leukemia Post Cytotoxic Therapy
    Juvenile Myelomonocytic Leukemia
    Mixed Phenotype Acute Leukemia
    Myelodysplastic Syndrome
    Myelodysplastic Syndrome Post Cytotoxic Therapy
    Myeloid Leukemia Associated With Down Syndrome

NCT04726241

LLS PedAL Initiative, LLC

16 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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