Necrotizing Fasciitis (NF) is a serious infection of the soft tissues, which can be life-threatening. This study is testing two ways to help heal the skin after NF: using a special fish skin graft called Acellular Fish Skin (AFS) and the usual treatment using Allograft Human Cadaver Skin (AHC). The study aims to see which method helps the skin heal faster before a permanent skin graft is applied.

This study is happening at the Joseph M. Still Burn Center and the Advanced Wound Clinic in Augusta. Patients who are 18 or older, have stable NF, and have had any necessary wound cleanings can participate. However, if you're pregnant, have an active autoimmune disease or cancer, you can't join the study.

• The study is single-center and you must visit either the Joseph M. Still Burn Center or the Advanced Wound Clinic.
• You must be at least 18 years old and have a stable NF wound.
• If you have been in another study or have wounds that can't fit a special wound care device, you can't participate.