This study is for people with gastrointestinal cancers, which are cancers that affect the stomach and intestines. It looks at whether receiving a chemotherapy drug called oxaliplatin over 6 hours instead of 2 hours helps reduce nerve damage, a side effect that can occur with this treatment. The study aims to keep patients on the regular dose of chemotherapy longer without delays.

Key Points:

• The study involves regular visits every 14 days for chemotherapy, which will be administered either over 2 or 6 hours.
• Participants will be followed up for assessment at 1, 3, 6, 12, and 18 months after treatment.
• Patients must meet specific health criteria and agree to use effective birth control if applicable during the study.

To be part of this study, you need to have a confirmed diagnosis of gastrointestinal cancer and be planning for at least 4 cycles of a chemotherapy regimen called FOLFOX6. You must also meet certain health requirements and agree to follow the study protocol. This study is not suitable for those with severe nerve damage or other certain health conditions. If you are pregnant or nursing, you cannot participate.