Neuroblastoma is a type of cancer that mostly affects children and starts in certain nerve tissues. This study aims to find better treatments and ways to stop the tumor from coming back. To achieve this, scientists will collect samples of neuroblastoma tissues, as well as blood and bone marrow cells, and store them in a bank. These samples will be studied to understand the characteristics of neuroblastoma cells better. The researchers will also gather clinical data, like treatment details and scans, to help with the laboratory studies. They will create cell lines from these samples, which are groups of cells that continue to grow in the lab. These will be shared with other researchers studying high-risk neuroblastoma.

Eligibility: To join the study, patients must be over 31 days old and have a diagnosis of high-risk neuroblastoma, which means the cancer is more severe. There are no exclusion criteria, meaning most eligible patients can participate.

• Participants must undergo evaluations and provide samples.
• No exclusion criteria mean broad eligibility.
• Samples will help develop new treatments.