This study is for women with gynecological cancers, like uterine or ovarian cancer, who are receiving a chemotherapy drug called paclitaxel. Paclitaxel can cause peripheral neuropathy, which is when you feel numbness, pain, or tingling in your hands and feet. The study tests if cryocompression therapy, which uses compression and cooling, with or without a medicine called cilostazol can help prevent this side effect. Cilostazol improves blood flow and might help reduce neuropathy symptoms. There are three groups: one gets paclitaxel with cryocompression and cilostazol, one gets paclitaxel with cryocompression only, and the last group gets standard care without these therapies. The study lasts for 6-9 cycles of treatment, with follow-ups up to a year.
- The study requires several visits for treatment and follow-up.
- Participants may experience common side effects of paclitaxel.
- Participants receive compensation for their time and travel.