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A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Exploring tetrodotoxin for chemotherapy-induced neuropathic pain relief.

Recruiting
21 years and older
All
Phase 2

Tetrodotoxin is a study drug being tested for its effects on neuropathic pain, which is pain caused by nerve damage. This trial is for people who have nerve pain due to chemotherapy treatment with drugs called platinum or taxane. Before joining, patients will have a screening period of up to 35 days to check if they are eligible. The trial includes a 4-day treatment period followed by a 12-week follow-up to observe changes in pain levels compared to a placebo (a harmless pill that has no effect).

To join, participants must be over 21, have stable nerve pain for at least 3 months, and not have any other serious health issues. They also must not have used certain drugs recently that might affect the study. People must agree to use birth control during the trial period.

  • The study lasts about 13 weeks after treatment starts.
  • No new treatments like chemotherapy or radiotherapy are allowed during the study.
  • Participation involves multiple visits and monitoring of pain levels.

This study does not mention any specific compensation for participants. If interested, check eligibility and discuss with your doctor.

Study details
    Chemotherapy-induced Neuropathic Pain
    Chemotherapy-induced Peripheral Neuropathy

NCT05359133

Wex Pharmaceuticals Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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