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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

Exploring radiotherapy for specific low-risk breast cancer types.

Recruiting
35 years and older
Female
Phase 3

This study aims to explore if women with low-risk breast cancer need regional radiation therapy. Typically, women receive treatment to stop cancer from coming back, which may include radiotherapy to the breast and nearby lymph nodes (regional radiotherapy). However, it's unclear if all women need this extra radiation, which can have side effects. The study will compare women receiving usual care, including regional radiotherapy, to those who do not receive it, to see if it makes a difference in preventing cancer's return.

Key Points:

  • Involves women with low-risk breast cancer; treatment may include surgery, chemotherapy, and hormone therapy.
  • Study tests if skipping regional radiation therapy is effective; may reduce exposure to unnecessary treatment.
  • Participants must be accessible for treatment and follow-up, and agree to provide tissue and blood samples for testing.
Study details
    Breast Cancer

NCT03488693

Canadian Cancer Trials Group

16 March 2025

Step 1 Get in touch with the nearest study center
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