This study is checking how well a medicine called nadofaragene firadenovec works for a type of bladder cancer called CIS (Carcinoma in Situ). If someone didn’t get better after the first dose of this medicine, they can try it again in the study. To join, you need to have a certain type of bladder cancer that hasn't spread to muscles and had a treatment called BCG (Bacillus Calmette Guerin) before. You can't join if your cancer has spread or if you've had other new treatments for bladder cancer. There are also some tests they will check to make sure your liver and kidneys are healthy enough.

• This study might be a second chance if the first dose didn't work.
• Your cancer type and past treatments matter for joining.
• Check with the doctor about your liver and kidney health before joining.