Image

Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder

Testing nerve stimulation for PTSD in veterans.

Recruiting
18-75 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study Overview: This study examines the effects of a treatment called transcutaneous cervical vagal nerve stimulation (tcVNS) on veterans with posttraumatic stress disorder (PTSD). tcVNS is a non-invasive way of stimulating the vagus nerve in the neck using a device outside the skin. Veterans will use this device at home twice a day for three months. The study will compare tcVNS with a fake treatment (sham) to see its effect on the brain, body, and PTSD symptoms.

What to Expect: All participants will undergo brain imaging using a special scan called High Resolution Positron Emission Tomography (HR-PET) and other tests before and after treatment. The study uses a safe type of water with a short lifespan for imaging, and a device called GammaCore for tcVNS, which has shown no bad effects in past studies.

  • The study lasts for three months with home treatment twice daily.
  • Participants must be veterans aged 18-75 with PTSD, but not have certain medical conditions.
  • There are no known risks associated with the tcVNS device used in the study.
Print
Study details
    Stress Disorders
    Post-Traumatic

NCT05517304

VA Office of Research and Development

10 October 2024

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.