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A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Join a study evaluating Syfovre's safety for geographic atrophy in AMD.

Recruiting
60 years and older
All
Phase N/A

This study looks at how safe and tolerable a medicine called Pegcetacoplan (also known as Syfovre) is for patients with Geographic Atrophy (GA). GA is a condition that damages part of the eye called the macula, often due to Age-Related Macular Degeneration (AMD). This study is observational, which means doctors will watch and record what happens without changing the treatment.

Key Points:

  • The study is for people aged 60 or older with GA in one or both eyes.
  • If you join, your eye will be checked using special imaging techniques to see how the treatment is working.
  • You cannot join if you've had other eye treatments recently or if you have other eye diseases like uveitis or glaucoma.

To join, you should have good vision (better than 20/200) and be able to give consent. You should not have had certain eye surgeries or treatments recently. If you have a history of allergies to the study medicine, you cannot participate. The study involves regular eye check-ups to ensure the safety and effectiveness of the treatment.

Study details
    Geographic Atrophy

NCT06161584

Apellis Pharmaceuticals, Inc.

2 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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