Image

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

Comparing Retatrutide and Semaglutide for Type 2 Diabetes management.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study aims to compare two medications, retatrutide and semaglutide, to see how well they work and how safe they are for people with Type 2 Diabetes who don't manage their blood sugar well with metformin. Type 2 Diabetes is a condition where the body doesn't use insulin properly, leading to high blood sugar. Metformin is a common medicine for diabetes, and some participants may also use an SGLT2 inhibitor, another type of diabetes medication that helps the kidneys remove sugar from the body. The study will last about 26 months and could include up to 24 visits to the study site.

  • This study lasts for 26 months with up to 24 visits.
  • Participants must have Type 2 Diabetes and stable weight.
  • People with Type 1 Diabetes or certain health issues cannot join.
Print
Study details
    Diabetes Mellitus
    Type 2

NCT06260722

Eli Lilly and Company

9 March 2025

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.