This study is checking if a special type of donor cell (called **Orca-Q**) is safe and works well for people getting a type of blood cancer treatment called **allogeneic hematopoietic cell transplant**. This is when a person receives blood stem cells from another person to treat their cancer. The study wants to see if this new method is good for patients between 18 and 65 years old who have certain blood cancers like leukemia or myelodysplastic syndromes.
Key points to consider:
- Study Visits: Participants will need to go through several health checks and visits to the doctor.
- Eligibility: You must not have had a prior transplant and must meet certain health criteria.
- Risks: There might be risks involved like infections or reactions to the donor cells.
To join, you must match certain health conditions and not have other major illnesses. If you are pregnant or breastfeeding, you cannot participate. This study is important to see if the Orca-Q grafts can help improve outcomes for people with these serious conditions.