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Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Exploring INBRX-106 alone and with Keytruda for advanced tumors.

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study tests a new cancer treatment with two drugs, INBRX-106 and Pembrolizumab (Keytruda®), for people with advanced cancers that can't be surgically removed. The research aims to find safe doses and learn how well these drugs work alone or together.

Eligibility: Adults 18 years or older with specific advanced cancers that haven’t responded to standard treatments can join. Some people with other health conditions or recent cancer treatments might not be able to participate.

  • This study might require multiple visits for treatment and check-ups.
  • Participants may receive the study drugs and be monitored for side effects and effectiveness.
  • There could be risks, such as side effects from the drugs, which will be discussed with you.

If you are considering joining, think about the time commitment, potential benefits, and possible risks. Discuss with your doctor if this study might be a good option for you. The study is open-label, meaning both you and the researchers will know which treatment you are receiving. This is a Phase 1/2 trial, which means it’s an early stage in testing the treatment's safety and best dose.

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Study details
    Solid Tumor
    Non-Small Cell Lung Cancer
    Head and Neck Cancer
    Melanoma
    Gastric Cancer
    Renal Cell Carcinoma
    Urothelial Carcinoma

NCT04198766

Inhibrx Biosciences, Inc

13 December 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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