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A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Researching satralizumab's effects on Thyroid Eye Disease.

Recruiting
18 years and older
All
Phase 3

This study is looking at how well a medicine called **satralizumab** works for people with **Thyroid Eye Disease (TED)**. Satralizumab is a special medicine that blocks a protein called **interleukin-6 (IL-6)**, which can help reduce swelling and pain in the eyes. The study wants to see if it's safe and effective to use. **Pharmacokinetics** means how the body absorbs and processes the medicine, and **pharmacodynamics** means how the medicine affects the body.

  • Participants must have TED and meet certain health criteria.
  • Those who need immediate eye surgery or have other serious eye problems might not be eligible.
  • Pregnant or breastfeeding women cannot join this study.

The study involves taking satralizumab through a small needle under the skin. Participants will be monitored to see how they respond to the treatment. The study will help doctors understand if satralizumab is a good option for treating TED. If you have TED and meet the criteria, you might consider joining to help advance research. Always discuss with your doctor to ensure it's right for you.

Study details
    Thyroid Eye Disease
    TED

NCT05987423

Hoffmann-La Roche

2 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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