This study looks at whether adding a drug called apalutamide to the usual treatment helps people with prostate cancer after surgery. Prostate cancer is a disease where cancer cells form in the prostate, a gland in men. After surgery, patients often receive radiation therapy (high-energy x-rays to kill cancer) and hormone therapy (to stop male hormones that help cancer grow). Apalutamide is a drug that may help stop these hormones from reaching cancer cells, like stopping a key from entering a lock.

In this study, patients will be split into two groups. One group will get the usual treatment, and the other group will also take apalutamide daily for up to two years. The study will see if the cancer stays away longer with apalutamide.

• Study Length: Up to 2 years with regular check-ups
• Visits Needed: Frequent visits during the study
• Potential Side Effects: Apalutamide may have side effects, and these will be monitored

You must have had prostate cancer surgery and meet other health requirements to join. Talk to your doctor to see if this study is right for you.