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Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease

Trial testing safety and effects of BMS-986446 for early Alzheimer's.

Recruiting
50-80 years
All
Phase 2

This study checks how well a medicine called BMS-986446 works for people with early Alzheimer's Disease (AD). Alzheimer's is a brain disease that makes it hard to remember things. The study also tests if the medicine is safe and if people can handle it well.

People who want to join need to have mild memory problems from Alzheimer's. They must have scores showing memory issues but still have some memory ability. They cannot join if they have other health problems affecting memory or if they can't safely have certain brain scans.

  • Duration: Participation involves multiple visits for assessments over a period of time.
  • Incentives: Compensation details may be available for participants.
  • Safety: The study ensures safety checks throughout the process.

Participants will help researchers learn more about this medicine and its effects on Alzheimer's. Always discuss with a doctor before joining any study.

Study details
    Alzheimer Disease
    Early Onset

NCT06268886

Bristol-Myers Squibb

31 May 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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