Image

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory Multiple Myeloma

Testing AZD0305 for relapsed/refractory multiple myeloma treatment options.

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

AZD0305 Study for Multiple Myeloma: This study tests a new drug, AZD0305, for people with relapsed/refractory multiple myeloma (RRMM), which is a type of blood cancer that comes back or doesn't respond to treatment. AZD0305 is given alone or with other cancer drugs to see if it is safe and works well. The study has two main parts: dose escalation to find a safe amount to give, and dose expansion to learn more about its effects. Participants must have tried at least three other treatments, including specific cancer drugs.

  • Participants must be 18 or older and have a specific performance status as per the ECOG scale.
  • Participants must have confirmed multiple myeloma and meet certain measurable disease criteria.
  • Participants cannot join if they have certain health problems like severe asthma, heart disease, or if they recently had certain transplants.

This study helps doctors understand how AZD0305 works in treating RRMM and if it could be a new option for patients. Participants will receive the drug through an IV (intravenous) method. Joining the study involves regular hospital visits for monitoring.

Print
Study details
    Multiple Myeloma

NCT06106945

AstraZeneca

2 March 2025

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.