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Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer

Trying Atovaquone for tough-to-treat ovarian cancer.

Recruiting
18 years and older
Female
Phase 2

This study is testing if a medicine called atovaquone can help treat patients with a specific kind of ovarian cancer that doesn't respond well to typical treatments. Atovaquone is usually used to treat certain infections and works by stopping the growth of tiny organisms that can cause pneumonia. Researchers want to see if atovaquone can work better than usual cancer treatments for this type of cancer.

Key Points:

  • Participants will take atovaquone by mouth and have tests like CT scans and biopsies during the study.
  • After finishing the treatment, patients will have follow-ups for 30 days, then every 6 months.
  • Only patients 18 or older with a specific type of ovarian cancer that didn't improve with usual treatment can join.

During this study, patients will take medicine and have regular check-ups to see how well the treatment works. The study hopes to find out if atovaquone is better than the usual treatments for this type of cancer. If you have this type of ovarian cancer and meet the study requirements, you might consider participating.

Study details
    Ovarian High Grade Serous Adenocarcinoma
    Platinum-Resistant Ovarian Carcinoma

NCT05998135

Emory University

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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