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A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Exploring NKT2152 for advanced kidney cancer treatment options.

Recruiting
18 years and older
All
Phase 1/2

This study involves a medicine called NKT2152 that may help people with advanced clear cell renal cell carcinoma (ccRCC), a type of kidney cancer. The study is divided into two parts:

Phase 1 aims to find the best dose of NKT2152 that patients can handle. This part is for adults who have tried other treatments that did not work. The medicine is taken by mouth every day.

Phase 2 will check if the medicine works well and is safe for the patients. Participants will be randomly given one of two doses to see which works better.

  • This study may require multiple visits and tests to check your health and progress.
  • Participants might experience side effects, as the treatment is still being tested.
  • Compensation is not mentioned, so discuss this with the study team.

To join, you must be at least 18 years old, able to walk a certain distance, and have a life expectancy of at least 3 months. You should not have any serious heart or lung issues, other cancers, or active infections. If you're interested, ensure you understand the requirements and discuss them with the study team.

Study details
    ccRCC
    Clear Cell Renal Cell Carcinoma
    Kidney Cancer
    Kidney Neoplasms
    Renal Cancer
    Renal Neoplasms
    Recurrent Renal Cell Carcinoma
    Metastatic Renal Cell Carcinoma
    Refractory Renal Cell Carcinoma
    Advanced Renal Cell Carcinoma
    Hypoxia
    Renal Cell Carcinoma
    Hypoxia Inducible Factor (HIF)
    HIF2α Inhibitor
    Hypoxia Inducible Factor 2 Alpha (HIF-2 Alpha)
    Hypoxia Inducible Factor 2α (HIF-2α)
    Clear Cell

NCT05119335

NiKang Therapeutics, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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