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Emergency Department-Initiated Buprenorphine Validation Network Trial

Join a study on buprenorphine use starting in the Emergency Department.

Recruiting
18 years and older
All
Phase 2

This study is about helping people with **opioid use disorder (OUD)** in the **Emergency Department (ED)**. OUD means someone has trouble controlling their opioid drug use. The study will test giving **buprenorphine (BUP)**, a medicine that helps with OUD. They will compare two types: **sublingual buprenorphine (SL-BUP)**, which is taken under the tongue, and **extended-release buprenorphine (XR-BUP)**, which lasts longer in the body. They want to see which one helps more people get into treatment after a week. They will also look at patients with mild or no withdrawal symptoms, using a tool called the **Clinical Opioid Withdrawal Scale (COWS)**. Lastly, they will create new ways to find and track OUD patients using hospital records.

  • The study includes about 30 EDs across the U.S.
  • Participants must be 18 years or older and meet certain criteria.
  • There are risks, like not getting the medicine that works best for you, but the study aims to improve OUD treatment.
Study details
    Opioid-use Disorder

NCT04225598

Yale University

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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