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Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Studying cooling duration impact on cardiac arrest recovery.

Recruiting
18 years and older
All
Phase N/A

Study Overview: This clinical trial aims to find the best cooling duration for patients who have had a cardiac arrest. Cardiac arrest is when the heart suddenly stops, affecting the brain too. Cooling, or "induced hypothermia," helps protect the brain during recovery. Researchers want to see if longer cooling times lead to better brain recovery.

Important Terms:

  • Cardiac Arrest: When the heart suddenly stops working.
  • Induced Hypothermia: Lowering the body temperature to protect the brain.
  • Neurological Outcomes: How well the brain recovers.

Study Details:

  • This study is at about 50 hospitals and will last 4 years.
  • Patients will be cooled for different times (6 to 72 hours) to find the best duration.
  • Consent is needed from a legal representative since participants are unconscious.

Eligibility: Adults who are unconscious after cardiac arrest and cooled within 240 minutes can join. People with unstable health or certain pre-existing conditions can't participate.

The trial will help improve the chances of brain recovery after a cardiac arrest. Participants must be enrolled within 6 hours of cooling. The goal is to find better ways to help people recover from this serious condition.

Study details
    Cardiac Arrest
    Out-Of-Hospital
    Hypothermia
    Induced
    Hypoxia-Ischemia
    Brain

NCT04217551

University of Michigan

19 January 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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