Image

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Trial testing DB-1303/BNT323 for advanced or metastatic solid tumors.

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new medicine, DB-1303/BNT323, for people with tough-to-treat cancers (called HER2-positive tumors). HER2 is a protein that can make cancer grow. The study is in two parts: the first part finds a safe dose, and the second part checks how well it works. The study involves taking this medicine multiple times and is happening at many places. You might join if your cancer can't be removed by surgery, keeps coming back, or has spread to other parts of your body.

  • Length: The study has two phases, and you may need to visit the study center multiple times.
  • Risks: There are risks like side effects from the new medicine.
  • Eligibility: You need to have a specific type of cancer and meet health criteria.

Note: Medical terms explained - Metastatic: cancer has spread; Refractory: doesn't respond to treatment; ECOG: a scale to measure daily living ability; LVEF: heart's pumping ability; CHF: heart failure.

Print
Study details
    HER2-positive Advanced Solid Tumor

NCT05150691

DualityBio Inc.

13 December 2024

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.